Regulatory
Part:BBa_K4942002
Designed by: Huang Xinqi Group: iGEM23_SHSID-China (2023-08-10)
luxI
BBa_K4942002 (luxI)
Profile
- Name: luxI
- Base Pairs: 582bp
- Origin: Aliivibrio logei, synthetic
- Properties: LuxI (LuxI-Family Autoinducer Synthase) is an enzyme that belongs to the LuxI family of autoinductive synthases. LuxI family enzymes are widely distributed in bacteria, especially Gram-negative bacteria.
Usage and Biology
LuxI enzyme plays a role in the synthesis of bacterial self-sensing signal molecules. These signaling molecules are usually N-acyl-Homoserine Lactone (AHL). Bacteria achieve quorum sensing and information sharing among bacterial populations by producing and detecting these signal molecules AHL. It is particularly important in biofilm formation and bacterial populations that cause biomass attachment. When the number of bacteria in the bacterial population reaches a certain threshold, LuxI catalyzes the conversion of substrates into AHL signaling molecules and leads to other bacterial sensing signals, thereby controlling the expression of specific genes[1].
Reference
- N M K, A S K, Ancha B, et al. A combination of luxR1 and luxR2 genes activates Pr-promoters of psychrophilic Aliivibrio logei lux-operon independently of chaperonin GroEL/ES and protease Lon at high concentrations of autoinducer. Biochemical and biophysical research communications, 2016, 473(4).
Sequence and Features
Assembly Compatibility:
- 10COMPATIBLE WITH RFC[10]
- 12COMPATIBLE WITH RFC[12]
- 21COMPATIBLE WITH RFC[21]
- 23COMPATIBLE WITH RFC[23]
- 25COMPATIBLE WITH RFC[25]
- 1000COMPATIBLE WITH RFC[1000]
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Categories
Parameters
None |